This article provides an overview of the 2022 ICD-10-CM code updates, including codes that were added, deleted, and revised, which went live on October 1, 2021.

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2022 ICD-10-CM Updates

The ICD-10-CM 2021 code set will be sunset January 1, 2022.

The 2022 ICD-10-CM Codes are pushed live on October 1, 2021.

  • 159 codes were added
  • 32 codes were deleted
  • 20 codes were revised

Here is a list of all of the codes that were altered:

Action ICD10 Code Code description
Added A7982 Anaplasmosis [A. phagocytophilum]
Added C563 Malignant neoplasm of bilateral ovaries
Added C7963 Secondary malignant neoplasm of bilateral ovaries
Added C847A Anaplastic large cell lymphoma, ALK negative, breast
Deleted D552 Anemia due to disorders of glycolytic enzymes
Added D5521 Anemia due to pyruvate kinase deficiency
Added D5529 Anemia due to other disorders of glycolytic enzymes
Added D75838 Other thrombocytosis
Added D75839 Thrombocytosis, unspecified
Added D8944 Hereditary alpha tryptasemia
Added E75244 Niemann-Pick disease type A/N
Added F32A Depression, unspecified
Deleted F78 Other intellectual disabilities
Added F78A1 SYNGAP1-related intellectual disability
Added F78A9 Other genetic related intellectual disability
Added G0482 Acute flaccid myelitis
Added G4486 Cervicogenic headache
Revise from G7120 Congenital myopathy unspecifed
Revise to G7120 Congenital myopathy unspecified
Delete G92 Toxic encephalopathy
Added G9200 Immune effector cell-associated neurotoxicity syndrome, grade unspecified
Added G9201 Immune effector cell-associated neurotoxicity syndrome, grade 1
Added G9202 Immune effector cell-associated neurotoxicity syndrome, grade 2
Added G9203 Immune effector cell-associated neurotoxicity syndrome, grade 3
Added G9204 Immune effector cell-associated neurotoxicity syndrome, grade 4
Added G9205 Immune effector cell-associated neurotoxicity syndrome, grade 5
Added G928 Other toxic encephalopathy
Added G929 Unspecified toxic encephalopathy
Added I5A Non-ischemic myocardial injury (non-traumatic)
Deleted K228 Other specified diseases of esophagus
Added K2281 Esophageal polyp
Added K2282 Esophagogastric junction polyp
Added K2289 Other specified disease of esophagus
Added K31A0 Gastric intestinal metaplasia, unspecified
Added K31A11 Gastric intestinal metaplasia without dysplasia, involving the antrum
Added K31A12 Gastric intestinal metaplasia without dysplasia, involving the body (corpus)
Added K31A13 Gastric intestinal metaplasia without dysplasia, involving the fundus
Added K31A14 Gastric intestinal metaplasia without dysplasia, involving cardia
Added K31A15 Gastric intestinal metaplasia without dysplasia, involving multiple sites
Added K31A19 Gastric intestinal metaplasia without dysplasia, unspecified site
Added K31A21 Gastric intestinal metaplasia with low grade dysplasia
Added K31A22 Gastric intestinal metaplasia with high grade dysplasia
Added K31A29 Gastric intestinal metaplasia with dysplasia, unspecified
Added L24A0 Irritant contact dermatitis due to friction or  contact with body fluids, unspecified
Added L24A1 Irritant contact dermatitis due to saliva
Added L24A2 Irritant contact dermatitis due to fecal, urinary or dual incontinence
Added L24A9 Irritant contact dermatitis related to friction or contact with other specified body fluids
Added L24B0 Irritant contact dermatitis related to unspecified stoma or fistula
Added L24B1 Irritant contact dermatitis related to digestive stoma or fistula
Added L24B2 Irritant contact dermatitis related to respiratory stoma or fistula
Added L24B3 Irritant contact dermatitis related to fecal or urinary stoma or fistula
Deleted M311 Thrombotic microangiopathy
Added M3110 Thrombotic microangiopathy, unspecified
Added M3111 Hematopoietic stem cell transplantation-associated thrombotic microangiopathy [HSCT-TMA]
Added M3119 Other thrombotic microangiopathy
Revised from M3500 Sicca syndrome, unspecified
Revised to M3500 Sjogren syndrome, unspecified
Revised from M3501 Sicca syndrome with keratoconjunctivitis
Revised to M3501 Sjogren syndrome with keratoconjunctivitis
Revised from M3502 Sicca syndrome with lung involvement
Revised to M3502 Sjogren syndrome with lung involvement
Revised from M3503 Sicca syndrome with myopathy
Revised to M3503 Sjogren syndrome with myopathy
Revised from M3504 Sicca syndrome with tubulo-interstitial nephropathy
Revised to M3504 Sjogren syndrome with tubulo-interstitial nephropathy
Added M3505 Sjogren syndrome with inflammatory arthritis
Added M3506 Sjogren syndrome with peripheral nervous system involvement
Added M3507 Sjogren syndrome with central nervous system involvement
Added M3508 Sjogren syndrome with gastrointestinal involvement
Revised from M3509 Sicca syndrome with other organ involvement
Revised to M3509 Sjogren syndrome with other organ involvement
Added M350A Sjogren syndrome with glomerular disease
Added M350B Sjogren syndrome with vasculitis
Added M350C Sjogren syndrome with dental involvement
Added M45A0 Non-radiographic axial spondyloarthritis of unspecified sites in spine
Added M45A1 Non-radiographic axial spondyloarthritis of occipito-atlanto-axial region
Added M45A2 Non-radiographic axial spondyloarthritis of cervical region
Added M45A3 Non-radiographic axial spondyloarthritis of cervicothoracic region
Added M45A4 Non-radiographic axial spondyloarthritis of thoracic region
Added M45A5 Non-radiographic axial spondyloarthritis of thoracolumbar region
Added M45A6 Non-radiographic axial spondyloarthritis of lumbar region
Added M45A7 Non-radiographic axial spondyloarthritis of lumosacral region
Added M45A8 Non-radiographic axial spondyloarthritis of sacral and sacrococcygeal region
Added M45AB Non-radiographic axial spondyloarthritis of multiple sites in spine
Deleted M545 Low back pain
Added M5450 Low back pain, unspecified
Added M5451 Vertebrogenic low back pain
Added M5459 Other low back pain
Added P0082 Newborn affected by (positive) maternal group B streptococcus (GBS) colonization
Deleted P09 Abnormal findings on neonatal screening
Added P091 Abnormal findings on neonatal screening for inborn errors of metabolism
Added P092 Abnormal findings on neonatal screening for congenital endocrine disease
Added P093 Abnormal findings on neonatal screening for congenital hematologic disorders
Added P094 Abnormal findings on neonatal screening for cystic fibrosis
Added P095 Abnormal findings on neonatal screening for critical congenital heart disease
Added P096 Abnormal findings on neonatal screening for neonatal hearing loss
Added P098 Other abnormal findings on neonatal screening
Added P099 Abnormal findings on neonatal screening, unspecified
Deleted R05 Cough
Added R051 Acute cough
Added R052 Subacute cough
Added R053 Chronic cough
Added R054 Cough syncope
Added R058 Other specified cough
Added R059 Cough, unspecified
Deleted R358 Other polyuria
Added R3581 Nocturnal polyuria
Added R3589 Other polyuria
Added R4588 Nonsuicidal self-harm
Deleted R633 Feeding difficulties
Added R6330 Feeding difficulties, unspecified
Added R6331 Pediatric feeding disorder, acute
Added R6332 Pediatric feeding disorder, chronic
Added R6339 Other feeding difficulties
Added R7983 Abnormal findings of blood amino-acid level
Added S06A0XA Traumatic brain compression without herniation, initial encounter
Added S06A0XD Traumatic brain compression without herniation, subsequent encounter
Added S06A0XS Traumatic brain compression without herniation, sequela
Added S06A1XA Traumatic brain compression with herniation, initial encounter
Added S06A1XD Traumatic brain compression with herniation, subsequent encounter
Added S06A1XS Traumatic brain compression with herniation, sequela
Added T40711A Poisoning by cannabis accidental (unintentional), initial encounter
Added T40711D Poisoning by cannabis, accidental (unintentional), subsequent encounter
Added T40711S Poisoning by cannabis, accidental (unintentional), sequela
Added T40712A Poisoning by cannabis, intentional self-harm, initial encounter
Added T40712D Poisoning by cannabis, intentional self-harm, subsequent encounter
Added T40712S Poisoning by cannabis, intentional self-harm, sequela
Added T40713A Poisoning by cannabis, assault, initial encounter
Added T40713D Poisoning by cannabis, assault, subsequent encounter
Added T40713S Poisoning by cannabis, assault, sequela
Added T40714A Poisoning by cannabis, undetermined, initial encounter
Added T40714D Poisoning by cannabis, undetermined, subsequent encounter
Added T40714S Poisoning by cannabis, undetermined, sequela
Added T40715A Adverse effect of cannabis, initial encounter
Added T40715D Adverse effect of cannabis, subsequent encounter
Added T40715S Adverse effect of cannabis, sequela
Added T40716A Underdosing of cannabis, initial encounter
Added T40716D Underdosing of cannabis, subsequent encounter
Added T40716S Underdosing of cannabis, sequela
Added T40721A Poisoning by synthetic cannabinoids, accidental (unintentional), initial encounter
Added T40721D Poisoning by synthetic cannabinoids, accidental (unintentional), subsequent encounter
Added T40721S Poisoning by synthetic cannabinoids, accidental (unintentional), sequela
Added T40722A Poisoning by synthetic cannabinoids, intentional self-harm, initial encounter
Added T40722D Poisoning by synthetic cannabinoids, intentional self-harm, subsequent encounter
Added T40722S Poisoning by synthetic cannabinoids, intentional self-harm sequela
Added T40723A Poisoning by synthetic cannabinoids, assault, initial encounter
Added T40723D Poisoning by synthetic cannabinoids, assault, subsequent encounter
Added T40723S Poisoning by synthetic cannabinoids, assault, sequela
Added T40724A Poisoning by synthetic cannabinoids, undetermined, initial encounter
Added T40724D Poisoning by synthetic cannabinoids, undetermined, subsequent encounter
Added T40724S Poisoning by synthetic cannabinoids, undetermined, sequela
Added T40725A Adverse effect of synthetic cannabinoids, initial encounter
Added T40725D Adverse effect of synthetic cannabinoids, subsequent encounter
Added T40725S Adverse effect of synthetic cannabinoids, sequela
Added T40726A Underdosing of synthetic cannabinoids, initial encounter
Added T40726D Underdosing of synthetic cannabinoids, subsequent encounter
Added T40726S Underdosing of synthetic cannabinoids, sequela
Deleted T407X1A Poisoning by cannabis (derivatives), accidental (unintentional), initial encounter
Deleted T407X1D Poisoning by cannabis (derivatives), accidental (unintentional), subsequent encounter
Deleted T407X1S Poisoning by cannabis (derivatives), accidental (unintentional), sequela
Deleted T407X2A Poisoning by cannabis (derivatives), intentional self-harm, initial encounter
Deleted T407X2D Poisoning by cannabis (derivatives), intentional self-harm, subsequent encounter
Deleted T407X2S Poisoning by cannabis (derivatives), intentional self-harm, sequela
Deleted T407X3A Poisoning by cannabis (derivatives), assault, initial encounter
Deleted T407X3D Poisoning by cannabis (derivatives), assault, subsequent encounter
Deleted T407X3S Poisoning by cannabis (derivatives), assault, sequela
Deleted T407X4A Poisoning by cannabis (derivatives), undetermined, initial encounter
Deleted T407X4D Poisoning by cannabis (derivatives), undetermined, subsequent encounter
Deleted T407X4S Poisoning by cannabis (derivatives), undetermined, sequela
Deleted T407X5A Adverse effect of cannabis (derivatives), initial encounter
Deleted T407X5D Adverse effect of cannabis (derivatives), subsequent encounter
Deleted T407X5S Adverse effect of cannabis (derivatives), sequela
Deleted T407X6A Underdosing of cannabis (derivatives), initial encounter
Deleted T407X6D Underdosing of cannabis (derivatives), subsequent encounter
Deleted T407X6S Underdosing of cannabis (derivatives), sequela
Revised from T63611A Toxic effect of contact with Portugese Man-o-war, accidental (unintentional), initial encounter
Revised to T63611A Toxic effect of contact with Portuguese Man-o-war, accidental (unintentional), initial encounter
Revised from T63611D Toxic effect of contact with Portugese Man-o-war, accidental (unintentional), subsequent encounter
Revised to T63611D Toxic effect of contact with Portuguese Man-o-war, accidental (unintentional), subsequent encounter
Revised from T63611S Toxic effect of contact with Portugese Man-o-war, accidental (unintentional), sequela
Revised to T63611S Toxic effect of contact with Portuguese Man-o-war, accidental (unintentional), sequela
Revised from T63612A Toxic effect of contact with Portugese Man-o-war, intentional self-harm, initial encounter
Revised to T63612A Toxic effect of contact with Portuguese Man-o-war, intentional self-harm, initial encounter
Revised from T63612D Toxic effect of contact with Portugese Man-o-war, intentional self-harm, subsequent encounter
Revised to T63612D Toxic effect of contact with Portuguese Man-o-war, intentional self-harm, subsequent encounter
Revised from T63612S Toxic effect of contact with Portugese Man-o-war, intentional self-harm, subsequent encounter
Revised to T63612S Toxic effect of contact with Portuguese Man-o-war, intentional self-harm, subsequent encounter
Revised from T63613A Toxic effect of contact with Portugese Man-o-war, assault, initial encounter
Revised to T63613A Toxic effect of contact with Portuguese Man-o-war, assault, initial encounter
Revised from T63613D Toxic effect of contact with Portugese Man-o-war, assault, subsequent encounter
Revised to T63613D Toxic effect of contact with Portuguese Man-o-war, assault, subsequent encounter
Revised from T63613S Toxic effect of contact with Portugese Man-o-war, assault, sequela
Revised to T63613S Toxic effect of contact with Portuguese Man-o-war, assault, sequela
Revised from T63614A Toxic effect of contact with Portugese Man-o-war, undetermined, initial encounter
Revised to T63614A Toxic effect of contact with Portuguese Man-o-war, undetermined, initial encounter
Revised from T63614D Toxic effect of contact with Portugese Man-o-war, undetermined, subsequent encounter
Revised to T63614D Toxic effect of contact with Portuguese Man-o-war, undetermined, subsequent encounter
Revised from T63614S Toxic effect of contact with Portugese Man-o-war, undetermined, sequela
Revised to T63614S Toxic effect of contact with Portuguese Man-o-war, undetermined, sequela
Added T8082XA Complication of immune effector cellular therapy, initial encounter
Added T8082XD Complication of immune effector cellular therapy, subsequent encounter
Added T8082XS Complication of immune effector cellular therapy, sequela
Added U099 Post COVID-19 condition unspecified
Added Y35899A Legal intervention involving other specified means, unspecified person injured, initial encounter
Added Y35899D Legal intervention involving other specified means, unspecified person injured, subsequent encounter
Added Y35899S Legal intervention involving other specified means, unspecified person injured sequela
Added Z555 Less than a high school diploma
Added Z586 Inadequate drinking-water supply
Deleted Z590 Homelessness
Added Z5900 Homelessness unspecified
Added Z5901 Sheltered homelessness
Added Z5902 Unsheltered homelessness
Deleted Z594 Lack of adequate food and safe drinking water
Added Z5941 Food insecurity
Added Z5948 Other specified lack of adequate food
Deleted Z598 Other problems related to housing and economic circumstances
Added Z59811 Housing instability, housed, with risk of homelessness
Added Z59812 Housing instability, housed, homelessness in past 12 months
Added Z59819 Housing instability, housed unspecified
Added Z5989 Other problems related to housing and economic circumstances
Added Z7185 Encounter for immunization safety counseling
Added Z91014 Allergy to mammalian meats
Deleted Z915 Personal history of self-harm
Added Z9151 Personal history of suicidal behavior
Added Z9152 Personal history of nonsuicidal self-harm
Revised from Z9225 Personal history of immunosupression therapy
Revised to Z9225 Personal history of immunosuppression therapy
Added Z92850 Personal history of Chimeric Antigen Receptor T-cell therapy
Added Z92858 Personal history of other cellular therapy
Added Z92859 Personal history of cellular therapy, unspecified
Added Z9286 Personal history of gene therapy

This article outlines the 2022 annual updates to ICD-10-CM codes, detailing revisions, additions, and deletions.

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